Sleep Nutrition Guide

What you eat, drink and take, and how it affects sleep.

Plain-language summaries of the evidence from NIH and the American Academy of Sleep Medicine, plus examples of clinical-grade supplements sold through healthcare professionals.

Important: this is education, not medical advice

SomniSmart is not a medical provider. Nothing here is meant to diagnose, treat, cure or prevent any disease, and supplements are not a substitute for treatment of sleep disorders. Talk to your doctor or pharmacist before starting any supplement, especially if you are pregnant or breastfeeding, take any medications, have a medical condition, or are considering anything for a child or teen. Ongoing insomnia, loud snoring, gasping at night or heavy daytime sleepiness deserve a medical evaluation; cognitive behavioural therapy for insomnia (CBT-I) is the recommended first treatment for chronic insomnia. The products on this page are sold through healthcare professionals: ask your provider before using any of them.

Why we only list practitioner-grade brands

Supplements are lightly regulated in the U.S. and quality varies. We feature only clinical-grade brands that sell mainly through healthcare professionals: Biotics Research, Standard Process, Metagenics, Designs for Health, Xymogen and Pure Encapsulations. These companies make their products under FDA current Good Manufacturing Practice (cGMP) rules and describe in-house or third-party testing for identity, potency and contaminants. Buying through a practitioner also means someone who knows your health history helps choose the product and dose. “Practitioner-grade” is not a government certification, and it does not make a supplement proven to work. The evidence sections below still apply.

These products are sold through healthcare professionals. Ask your provider whether one is right for you; many need a practitioner account, referral or dispensary invitation (for example Fullscript), so prices are set by your practitioner.

Some links are affiliate links; they never change what we recommend. Disclosure.

Jump to: Timing and habits · Practitioner sleep formulas · Magnesium · Melatonin · Tart cherry · Glycine · L-theanine

Start here: timing and habits

Evidence: strongest for everyday changes
  • Caffeine: in a controlled study, 400 mg of caffeine taken even 6 hours before bed reduced total sleep by more than an hour. Try a caffeine cut-off at least 6 hours before bedtime (many people do better with a noon cut-off). Remember tea, cola, energy drinks, pre-workout and dark chocolate.
  • Alcohol: it can make you fall asleep faster, but a review of the research found it disrupts sleep in the second half of the night and reduces REM sleep, with bigger effects at higher doses. Avoid using a “nightcap” as a sleep aid and leave a few hours between your last drink and bed.
  • Meals: avoid large, heavy or spicy meals right before bed, especially if you get reflux; a light snack is fine if hunger keeps you up.
  • Fluids: taper drinks in the last hour or two if you wake to use the bathroom.
  • Consistency beats supplements: a regular wake time, morning daylight and a cool, dark bedroom do more for most people than any pill.

Sources: Drake et al., J Clin Sleep Med 2013 (caffeine 0, 3 or 6 h before bed); Ebrahim et al., Alcohol Clin Exp Res 2013 (alcohol and sleep review)

Magnesium (glycinate / bisglycinate)

Evidence: limited

Magnesium is an essential mineral, and many adults get less than recommended from food. For sleep specifically, NIH’s NCCIH says the evidence is limited and of low quality. Glycinate (bisglycinate) forms are popular because they are generally gentler on the stomach than oxide or citrate.

  • Food first: leafy greens, legumes, nuts, seeds and whole grains.
  • The upper limit for supplemental magnesium in adults is 350 mg/day unless a clinician advises otherwise. Too much can cause diarrhoea and cramping.
  • Ask a doctor first if you have kidney disease, or take antibiotics, bisphosphonates, diuretics or acid-reducing drugs, because magnesium can interact with them.

Metagenics Magnesium Glycinate (tablets)

Form / dose: 1 tablet = 100 mg magnesium; label suggests 1 tablet three times daily (300 mg).

Key ingredients: Magnesium as magnesium bis-glycinate.

Price via practitioner. Metagenics is sold through healthcare practitioners, or a practitioner’s Metagenics or Fullscript online store.

View product details →

Standard Process Magnesium Lactate (tablets)

Form / dose: 2 tablets = 200 mg magnesium.

Key ingredients: Magnesium lactate.

Price via practitioner. Standard Process sells through healthcare professionals; order through your practitioner or their online dispensary.

View product details →

Standard Process E-Z Mg™ (tablets)

Form / dose: 6 tablets = 70 mg magnesium (a low, food-based dose).

Key ingredients: Organic Swiss chard and buckwheat juice powders (plant-sourced magnesium).

Price via practitioner. Standard Process sells through healthcare professionals; order through your practitioner or their online dispensary.

View product details →

Sources: NIH Office of Dietary Supplements: Magnesium fact sheet; NCCIH: Sleep disorders and complementary health approaches

Melatonin (low dose)

Evidence: helps for jet lag and some timing problems; not recommended for chronic insomnia

Melatonin is a hormone that signals “night” to your body clock. It is most useful for shifting sleep timing (jet lag, delayed sleep phase), not as a nightly sedative. The American Academy of Sleep Medicine’s insomnia guideline suggests against melatonin for chronic insomnia in adults.

  • More is not better: many sleep clinicians start with 0.5–1 mg, taken a few hours or 30–60 minutes before your target bedtime depending on the goal. Ask your doctor what dose and timing fit you.
  • In the U.S. melatonin is sold as a supplement, and tested products have contained very different amounts than their labels state. Choose a manufacturer that tests its products and documents it, and ask your provider which one to use.
  • Children and teens: the AASM advises talking to a pediatric clinician before giving melatonin; melatonin overdoses in children have risen sharply.
  • Ask a doctor first if you are pregnant or breastfeeding, have epilepsy or an autoimmune condition, or take blood thinners, blood-pressure, diabetes or immune-suppressing medicines.

Low-dose options: the practitioner products below come in 0.5 mg and 1.5 mg servings. Your provider can tell you which dose and timing suit your goal.

Pure Encapsulations Melatonin 0.5 mg (capsules)

Form / dose: 1 capsule = 0.5 mg melatonin, ½–1 hour before bed per label.

Key ingredients: Melatonin only; cellulose capsule.

Price via practitioner. Dispensed through practitioners on Fullscript (needs a practitioner invitation). Pure Encapsulations is a professional-grade brand that is also sold to consumers directly.

View product details →

Biotics Research Melatonin-B6/Mg (tablets)

Form / dose: ½ tablet = 1.5 mg melatonin per the brand’s serving size; follow the label and your provider’s directions.

Key ingredients: Melatonin, vitamin B6 (as P-5-P), magnesium (as glycinate).

Price via practitioner. Biotics Research is sold through healthcare professionals; the brand shop requires a practitioner account or referral.

View product details →

Sources: NCCIH: Melatonin, what you need to know; AASM health advisory: melatonin use in children and adolescents; Rishi et al., J Clin Sleep Med 2023; Sateia et al., AASM insomnia pharmacologic guideline, J Clin Sleep Med 2017

Tart cherry

Evidence: early / small studies

Tart (Montmorency) cherries contain small amounts of melatonin and polyphenols. A small pilot study in 15 older adults with insomnia found modest improvements with tart cherry juice twice daily versus placebo. Promising, but the studies are small. Watch the sugar and calories in juice, and ask a doctor if you have diabetes or take blood thinners.

No practitioner pick yet: we did not find a tart-cherry product for sleep from the practitioner brands we cover (Biotics Research, Standard Process, Metagenics, Designs for Health, Xymogen, Pure Encapsulations, Integrative Therapeutics, Ortho Molecular). Practitioner cherry products we found are either sweet cherry or formulated for other purposes. Whole tart cherries or 100% tart cherry juice are a food option; ask your provider, especially if you have diabetes.

Sources: Pigeon et al., J Med Food 2010

Glycine

Evidence: early / small studies

Glycine is an amino acid. Small Japanese studies found 3 g before bed improved how rested people felt and slightly shortened the time to fall asleep. The evidence comes from few, small trials. Ask a doctor first if you take clozapine or other antipsychotics.

Designs for Health Glycine Powder

Form / dose: 1 scoop ≈ 3 g glycine (the dose used in the sleep studies above).

Key ingredients: Free-form glycine.

Price via practitioner. Designs for Health is sold through healthcare practitioners.

View product details →

Sources: Yamadera et al., Sleep and Biological Rhythms 2007

L-theanine

Evidence: mixed; small benefits

L-theanine is an amino acid found in tea. A 2025 systematic review and meta-analysis found small improvements in some sleep measures, with mixed results across studies. It may suit people whose sleep is disturbed by a busy mind. Ask a doctor first if you take blood-pressure medicines or stimulants.

Xymogen L-Theanine (capsules)

Form / dose: Label suggests 1–2 capsules twice daily; the per-capsule amount is on the product label (listed by dispensaries as 200 mg Suntheanine®).

Key ingredients: L-theanine as Suntheanine®.

Price via practitioner. Xymogen is sold exclusively through licensed healthcare professionals.

View product details →

Sources: Bulman et al., Sleep Med Rev 2025 (PubMed 40056718)

Practitioner sleep formulas

Evidence: varies by ingredient; combination products are rarely studied as a whole

Practitioners often use combination formulas. Their individual ingredients have mixed evidence (melatonin and L-theanine above; valerian and passionflower have small, inconsistent studies), and the combined products themselves have generally not been tested in large trials. Herbal sedatives can add to the effects of alcohol, sleep medicines and some antidepressants, so check with your provider and pharmacist.

Metagenics Benesom® (tablets)

Form / dose: Label suggests 1–2 tablets about 30 minutes before sleep; contains 3 mg melatonin per labelled serving.

Key ingredients: Melatonin 3 mg, magnesium 140 mg (as citrate), calcium 70 mg, Chinese skullcap root extract 400 mg, passionflower 200 mg, lemon balm 150 mg, valerian root extract 100 mg, hops 50 mg. Label: adults only, not for pregnancy or nursing, avoid with sedating medicines or alcohol.

Price via practitioner. Metagenics is sold through healthcare practitioners, or a practitioner’s Metagenics or Fullscript online store.

View product details →

Biotics Research SleepTides™ (capsules)

Form / dose: 1 capsule 30 minutes before bed.

Key ingredients: PeptiSleep™ rice protein hydrolysate (plant peptides from brown rice).

Price via practitioner. Biotics Research is sold through healthcare professionals; the brand shop requires a practitioner account or referral.

View product details →

Biotics Research Alpha-Theta Ultra PM™ (capsules)

Form / dose: 2 capsules before bed; per-ingredient amounts are on the product label (not shown on the brand page).

Key ingredients: L-theanine (Suntheanine®), Baikal skullcap, lemon balm, passionflower, 5-HTP, melatonin, vitamin B6 (P-5-P). Label: not for children or pregnancy/lactation; do not mix with alcohol, sedatives or stimulants. 5-HTP can interact with antidepressants.

Price via practitioner. Biotics Research is sold through healthcare professionals; the brand shop requires a practitioner account or referral.

View product details →

Standard Process MediHerb® Valerian Complex (tablets)

Form / dose: 1 tablet 2–4 times daily per label.

Key ingredients: Per tablet: valerian root & rhizome 5:1 extract 140 mg, passionflower 5:1 extract 100 mg, jujube seed 10:1 extract 90 mg. Label: not for pregnancy or lactation unless directed by a professional.

Price via practitioner. Standard Process sells through healthcare professionals; order through your practitioner or their online dispensary.

View product details →

Product names, doses and ingredients from each brand’s official product page (or its practitioner dispensary listing), checked Oct 2026. Always follow the label on the bottle you receive and your provider’s directions. Prices are set by your practitioner or dispensary.